Professor Michael Phelps
Michael Phelps, the Norton Simon Professor and Chair of the UCLA Department of Molecular and Medical Pharmacology, has been on the faculty of the University of California since 1976. He is actively engaged in medical research, educational programs and multimedia technologies at UCLA. Dr. Phelps uniquely holds six academic positions at UCLA. In addition to serving as the Departmental Chairman and holding an endowed professorship, he is also the Director of the Crump Institute for Molecular Imaging, Professor of Biomathematics, the Director of the Institute for Molecular Medicine and the Chief of Nuclear Medicine.
He has received numerous awards, among them, the 1992 Pasarow Foundation Award, the 1987 Rosenthal Foundation Award of the American College of Physicians, the George Von Hevesy Prize (won twice) from the Von Hevesy Foundation in Zurich (Von Hevesy won the Nobel Prize in Chemistry), the 1984 Sarah L. Poiley Memorial Award from the New York Academy of Sciences, the 1984 Ernest O. Lawrence Presidential Award, the 1983 Paul Aebersold Award from the Society of Nuclear Medicine, chaired the 1983 Nobel Symposium, elected to the Institute of Medicine of the National Academy of Sciences in 1985, Enrico Fermi Presidential Award, 1998, elected to the National Academy of Sciences in 1999.
Dr. Phelps is the original inventor of PET (Positron Emission Tomography). PET is a molecular imaging technique that provides in vivo images of biological processes, blood flow, metabolism, cell communication systems, drug interactions and gene expression. PET is used in research to study the biological basis of normal organ function and the biological basis of disease. It is also routinely used as a clinical service in the early detection, characterization and evaluation of the therapeutic responses in cancer, neurological disorders and cardiovascular disease.
He has published over 520 scientific papers and books, dealing with such diverse topic
Hood, L., Heath, J.R., Phelps, M.E., Lin B. "Systems Biology and New Technologies Enable Predictive and Preventative Medicine". Science 2004; 306: 640-643.
Heath, J.R., Phelps, M.E., Hood, L. NanoSystems Biology. Molec Imag Biol 2003; 5: 312-325.
Ray P, Pimenta H, Paulmurugan R, Berger F, Phelps ME, Iyer M, Gambhir SS Noninvasive quantitative imaging of protein-protein interactions in living subjects.. Proc Natl Acad Sci 2002; 99(5): 3105-3110.
Liang Q, Gotts J, Satyamurthy S, Barrio J, Phelps ME, Gambhir SS, Herschman HR Noninvasive, repetitive, quantitative measurement of gene expression from a bicistronic message by positron emission tomography, following gene transfer with adenovirus.. Molec Therapy 2002; 6: 73-82.
Silverman DH, Small GW, Chang C, Lu CS, Kung de Auburto M, Chen W, Czernin J, Rapoport SI, Pietrini P, Alexander GE, Schapiro MB, Jagust WJ, Hoffman J, Welsh-Bohmer K, Alavi A, Clark CM, Salmon E, deLeon M, Mielke R, Cummings J, Kowell A, ... Positron emission tomography in evaluation of dementia: regional brain metabolism and long term outcome.. J Amer Med Assoc 2001; 286: 2120-2127.
Wu AM, Yazaki PJ, Tsai S, Nguyen K, Anderson AL, McCarthy DW, Welch MJ, Shively JE, Williams LE, Raubitschek AA, Wong JYC, Toyokuni T, Phelps ME, Gambhir SS High-resolution microPET imaging of carcino-embryonic antigen-positive xenografts by using a copper-64-labeled engineered antibody fragment.. Proc Nat'l Acad Sci 2000; 97: 8495-8500.
Phelps ME. Positron emission tomography provides molecular imaging of biological processes.. Proc Nat'l Acad Sci 2000; 97: 9226-9233.